Measurement of the subcutaneous fat in the distal forearm by single photon absorptiometry
The influence of subcutaneous fat on single photon (/sup 125/I) absorptiometry (SPA) measurement of bone mineral content of the distal forearm was investigated. A fat correction model was tested by measurements on eight lean subjects with different amounts of porcine fat around their forearm, and further validated from measurements on 128 females. In addition, it is shown that the fat content in the distal forearm can be measured by SPA with a short-term precision at 1.9% in an obese subject and that it correlates well with total body fat (r2 = .7) measured by dual photon absorptiometry, skinfold thickness (r2 = .5), and body mass index (r2 = .6). By using this method in a double-blind placebo-controlled trial, hormonal substitutional therapy significantly decreased the forearm fat content without affecting the body weight in postmenopausal osteoporotic women.
- Research Organization:
- Univ. of Copenhagen (Denmark)
- OSTI ID:
- 6270656
- Journal Information:
- Metab., Clin. Exp.; (United States), Vol. 38:2
- Country of Publication:
- United States
- Language:
- English
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ACCURACY
ARMS
IODINE 125
MATHEMATICAL MODELS
MINERALS
OSTEOPOROSIS
SKELETON
VALIDATION
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
COMPUTERIZED TOMOGRAPHY
CONNECTIVE TISSUE
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ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
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ISOTOPES
LIMBS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
SKELETAL DISEASES
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550601* - Medicine- Unsealed Radionuclides in Diagnostics