MS/MS analysis of the products of toluene photooxidation and measurement of their mutagenic activity

Journal Article · Wed Nov 30 23:00:00 EST 1988 · Environ. Sci. Technol.; (United States)

DOI:https://doi.org/10.1021/es00177a017· OSTI ID:6259804

Dumdel, B E; Kenny, D V; Shepson, P B; Kleindienst, T E; Nero, C M; Cupitt, L T; Claxton, L D

Products of the photooxidation of toluene from an irradiated 5.1 ppm toluene/0.9 ppm NO/sub x/ mixture were identified by use of a triple-quadrupole MS/MS operated in an atmospheric pressure ionization mode. The reaction was carried out in a flow-mode 22.7-m/sup 3/ Telfon smog chamber. The steady-state reactant and product mixture was continuously transferred to the mass spectrometer inlet at 144 L/min. By using structurally similar standards, semiquantitative MS/MS analyses for many of the ring fragmentation products were conducted. Quantitative analyses by chromatographic methods and semiquantitative analyses by MS/MS were conducted for a variety of ring fragmentation products. The following products were found with yields of 1% (C/C) or greater: methylglyoxal, glyoxal, benzaldehyde, methylbutenedial, hydroxy-methylbutenedial, peroxyacetyl nitrate, oxoheptadienal, CH/sub 3/COOH, HCHO, hexadienal, and hydroxyoxo-heptadienal. The mutagenic activity of the steady-state product mixture was measured by using the Ames assay Salmonella typhimurium strain TA 100. The mutagenic activity data are discussed relative to our earlier findings that resulted from different reaction conditions.

• Research Organization: MDS Advanced Analytics, Inc., Andover, ME (USA)
• OSTI ID: 6259804
• Journal Information: Environ. Sci. Technol.; (United States), Journal Name: Environ. Sci. Technol.; (United States) Vol. 22:12; ISSN ESTHA
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AIR POLLUTION
ALKYLATED AROMATICS
AROMATICS
BACTERIA
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CHROMATOGRAPHY
DISPERSIONS
HYDROCARBONS
LIQUID COLUMN CHROMATOGRAPHY
MASS SPECTROSCOPY
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PHOTOCHEMICAL REACTIONS
POLLUTION
SALMONELLA
SALMONELLA TYPHIMURIUM
SCREENING
SEPARATION PROCESSES
SPECTROSCOPY
TOLUENE