Retention of aerosol particles in the human respiratory tract as a function of particle radius

Journal Article · Thu Jan 01 04:00:00 EST 1948 · J. Ind. Hyg. Toxicol.; (United States)

OSTI ID:6251647

Wilson, I B; LaMer, V K

A water--glycerol aerosol of /sup 24/NaCl (approx. 500 mg/m/sup 3/) was inhaled by 7 volunteers to assess retention of monodispersed aerosols in human respiratory tract. Various particle sizes were tested; dispersion method was thought to be effective. Alveolar retention shows two peaks in the 0.3 to 1 ..mu..m range. Maximum alveolar retention is approx. 45%. Total retention decreased linearly with breathing rate, increased linearly with radius from 0.2 to 1.6 ..mu..m.

• OSTI ID: 6251647
• Journal Information: J. Ind. Hyg. Toxicol.; (United States), Journal Name: J. Ind. Hyg. Toxicol.; (United States) Vol. 30; ISSN JIHTA
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
AIR POLLUTION
ANIMALS
BODY
COLLOIDS
DISPERSIONS
INHALATION
INTAKE
LUNGS
MAMMALS
MAN
ORGANS
PARTICLE SIZE
PARTICLES
POLLUTION
PRIMATES
RESPIRATORY SYSTEM
RETENTION
SIZE
SOLS
VERTEBRATES