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Trace metals and coronary heart disease risk indicators in 152 elderly men (the Zutphen study)

Journal Article · · Am. J. Epidemiol.; (United States)
OSTI ID:6239926
; ; ; ; ; ;
Information about trace metals and coronary heart disease risk indicators was collected in 1977 among 152 men aged 57-76 years in the town of Zutphen, the Netherlands. Serum zinc, serum copper, blood cadmium, and blood lead were determined by atomic absorption spectrometry and serum lithium by flame emission spectrometry. After uni- and multivariate regression analysis, the following statistically significant relations were found: serum zinc was inversely related to resting heart rate; serum copper was positively related to cigarette smoking and inversely to high density lipoprotein cholesterol; blood cadmium was strongly positively related to cigarette smoking and inversely to Quetelet index; the positive relation between blood lead and cigarette smoking was of borderline significance; and blood lead was related to blood pressure, with the relation being stronger for systolic than for diastolic blood pressure.
Research Organization:
State Univ. of Leiden, Netherlands
OSTI ID:
6239926
Journal Information:
Am. J. Epidemiol.; (United States), Journal Name: Am. J. Epidemiol.; (United States) Vol. 122:3; ISSN AJEPA
Country of Publication:
United States
Language:
English

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Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
AEROSOLS
AGED ADULTS
ALKALI METALS
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD SERUM
BODY FLUIDS
CADMIUM
CARDIOVASCULAR DISEASES
COLLOIDS
COPPER
CORRELATIONS
DISEASES
DISPERSIONS
ECOLOGICAL CONCENTRATION
ELEMENTS
EMISSION SPECTROSCOPY
EPIDEMIOLOGY
ETIOLOGY
EUROPE
HYPERTENSION
LEAD
LITHIUM
MALES
MAMMALS
MAN
MATERIALS
MATHEMATICS
MEN
METALS
NETHERLANDS
PRIMATES
REGRESSION ANALYSIS
RESIDUES
RISK ASSESSMENT
SMOKES
SOLS
SPECTROSCOPY
STATISTICS
SYMPTOMS
TOBACCO SMOKES
TRANSITION ELEMENTS
VASCULAR DISEASES
VERTEBRATES
WESTERN EUROPE
ZINC