Brain sarcoma of meningeal origin after cranial irradiation in childhood acute lymphocytic leukemia. Case report

Journal Article · Mon Oct 01 04:00:00 EDT 1984 · J. Neurosurg.; (United States)

DOI:https://doi.org/10.3171/jns.1984.61.4.0772· OSTI ID:6239787

Tiberin, P; Maor, E; Zaizov, R; Cohen, I J; Hirsch, M; Yosefovich, T; Ronen, J; Goldstein, J

The authors report their experience with an unusual case of intracerebral sarcoma of meningeal cell origin in an 8 1/2-year-old girl. This tumor occurred 6 1/2 years after cranial irradiation at relatively low dosage (2200 rads) had been delivered to the head in the course of a multimodality treatment for acute lymphocytic leukemia. The tumor recurred approximately 10 months after the first surgical intervention. Macroscopic total excision of the recurrent growth followed by whole-brain irradiation (4500 rads) failed to eradicate it completely and local recurrence prompted reoperation 18 months later. This complication of treatment in long-term childhood leukemia survivors is briefly discussed, as well as the pathology of meningeal sarcomas.

• Research Organization: Soroka Univ. Hospital, Beer-Sheba, Israel
• OSTI ID: 6239787
• Journal Information: J. Neurosurg.; (United States), Journal Name: J. Neurosurg.; (United States) Vol. 61:4; ISSN JONSA
• Country of Publication: United States
• Language: English

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