Clinical comparison of /sup 99m/Tc--diethyl-iminodiacetic acid, /sup 99m/Tc--pyridoxylideneglutamate, and /sup 131/I-rose bengal in liver transplant patients

Journal Article · Thu Feb 01 00:00:00 EST 1979 · Radiology; (United States)

OSTI ID:6204676

Klingensmith, W C; Fritzberg, A R; Koep, L J; Ronai, P M

The relative merits of three radiopharmaceuticals for evaluating liver transplant patients were determined in paired studies. In 86% of studies both /sup 131/I--RB and /sup 99m/Tc--PG gave similar information for differentiation of hepatocellular disease and biliary tract obstruction. /sup 99m/Tc--PG probably demonstrates the biliary tract and small intestine better early after injection (8%); /sup 131/I-RB is probably better in showing the colon at 24 hs when intestinal activity is not seen by 1 h (6%). /sup 99m/Tc--diethyl--IDA is superior in all respects when compared to /sup 99m/Tc--PG. The blood retention method (20 min./5 min.) showed that none of the radiopharmaceuticals was a reliable indicator of hepatocyte function when compared to total serum bilirubin.

• Research Organization: Univ. of Colorado Medical Center, Denver
• OSTI ID: 6204676
• Journal Information: Radiology; (United States), Vol. 130:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
ACETIC ACID ESTERS
RADIOPHARMACEUTICALS
BILIARY TRACT
DYNAMIC FUNCTION STUDIES
SCINTISCANNING
IMIDES
IODINE 131
LIVER
PYRIDOXYLIDENEGLUTAMATE
COMPARATIVE EVALUATIONS
ROSE BENGAL
SMALL INTESTINE
TECHNETIUM 99
TRANSPLANTS
INTRAVENOUS INJECTION
ISOMERIC NUCLEI
LABELLED COMPOUNDS
PATIENTS
AMINO ACIDS
AZINES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACID ESTERS
CARBOXYLIC ACIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DRUGS
DYES
ESTERS
GASTROINTESTINAL TRACT
GLANDS
GLUTAMIC ACID
HETEROCYCLIC COMPOUNDS
HOURS LIVING RADIOISOTOPES
HYDROXY ACIDS
INDICATORS
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
INTESTINES
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC IODINE COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRIDINES
RADIOACTIVE MATERIALS
RADIOISOTOPE SCANNING
RADIOISOTOPES
REAGENTS
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques
550901 - Pathology- Tracer Techniques