Optimal operating policy of the ultrafiltration membrane bioreactor for enzymatic hydrolysis of cellulose

Journal Article · Sun Sep 05 04:00:00 EDT 1993 · Biotechnology and Bioengineering; (United States)

DOI:https://doi.org/10.1002/bit.260420609· OSTI ID:6204385

Lee, SeungGoo; Kim, HakSung ^[1]

---

1. Korea Advanced Inst. of Science and Technology, Taejon (Korea, Republic of). Dept. of Biotechnology

The dilution rate of an ultrafiltration membrane bioreactor in the enzymatic hydrolysis of cellulose was optimized using the kinetic model developed by Fan and Lee.' The sequence of optimal dilution rates was found to generally consist of an initial period of a minimal value (batch period), a subsequent period of maximum dilution rate, a period of a second batch, and a final period of a singular dilution rate. The effects of operating conditions, such as [beta]-glucosidase activity, operating time, maximum dilution rate, substrate feeding rate, and enzyme-to-substrate ratio on both the conversion yield and the sequence of optimal dilution rates were investigated. To evaluate the validity of kinetic model employed in this work, enzymatic hydrolysis was carried out using -cellulose as a substrate in the ultrafiltration membrane bioreactor. The experimental data were well consistent with the simulation results.

• OSTI ID: 6204385
• Journal Information: Biotechnology and Bioengineering; (United States), Journal Name: Biotechnology and Bioengineering; (United States) Vol. 42:6; ISSN BIBIAU; ISSN 0006-3592
• Country of Publication: United States
• Language: English

Related Subjects

09 BIOMASS FUELS
090900* -- Biomass Fuels-- Processing-- (1990-)
BIOREACTORS
CARBOHYDRATES
CELLULOSE
CHEMICAL REACTIONS
DECOMPOSITION
EFFICIENCY
ENZYMATIC HYDROLYSIS
FILTRATION
HYDROLYSIS
LYSIS
MATHEMATICAL MODELS
OPTIMIZATION
ORGANIC COMPOUNDS
POLYSACCHARIDES
SACCHARIDES
SEPARATION PROCESSES
SOLVOLYSIS
ULTRAFILTRATION