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Resection followed by vascularized bone autograft in patients with possible recurrence of malignant bone tumors after conservative treatment

Journal Article · · J. Pediatr. Surg.; (United States)
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In conservative treatment of malignant bone tumors, assessment of the local condition is difficult. The radiological changes seen in the irradiated tumor and the frequent occurrence of pathological fractures at this site may give rise to the fear that the tumor has relapsed. Resection of the whole of the involved bone is the best way to assure adequate local control but the extent of the bone defect and the bad local conditions secondary to irradiation make reconstruction hazardous. In two patients (one with Ewing's sarcoma of the femur and one with osteogenic sarcoma of the humerus) the authors used a free, vascularized fibular graft for the reconstruction having obtained consolidation of the limb after resection of the irradiated tumor, with preservation of its function. The encouraging results obtained have suggested a conservative attitude as primary treatment of specific malignant bone tumors.

Research Organization:
Centre Hospitalier Regional 29, Nancy, France
OSTI ID:
6201404
Journal Information:
J. Pediatr. Surg.; (United States), Journal Name: J. Pediatr. Surg.; (United States) Vol. 19:2; ISSN JPDSA
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
BONE FRACTURES
DELAYED RADIATION EFFECTS
DISEASES
INJURIES
LIMBS
LOCAL RADIATION EFFECTS
MEDICINE
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OSTEORADIONECROSIS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SARCOMAS
SIDE EFFECTS
SKELETAL DISEASES
SKELETON
SURGERY
THERAPY