Routine clinical estimation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in the treatment of carcinoma of the cervix. [X ray; /sup 137/Cs]

Conference · Fri May 01 04:00:00 EDT 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

OSTI ID:6195487

Cunningham, D E; Stryker, J A; Velkley, D E; Chung, C K

An evaluation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in carcinoma of the cervix has been initiated on a routine basis in an effort to obtain the optimum radiotherapeutic dose. Contrast radiography on a radiotherapy simulator is used to image the rectum and bladder, and dose rates are determined at predesignated reference points with the aid of computer calculated dose distributions. Forty-three patients have been reviewed in order to ascertain the correlation between radiation injury and dose at reference points in the rectum and bladder. In a related study involving 77 patients, the doses at points A and B and the prescription in mghr were analyzed in relation to radiation injury. There was no apparent association between the incidence of radiation injury in either the mghr prescription or the doses at points A or B. Computer calculations were supplemented with in vivo and in vitro thermoluminescent dosimeter (TLD) measurements. We conclude that routine contrast radiography of the rectum and the bladder with dose calculations at selected reference points provides important information for optimizing radiotherapy in carcinoma of the cervix without a significant increase in treatment planning effort or patient discomfort.

• Research Organization: Pennsylvania State Univ., Hershey
• OSTI ID: 6195487
• Conference Information: Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Journal Volume: 7:5
• Country of Publication: United States
• Language: English

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560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
CARCINOMAS
CESIUM 137
CESIUM ISOTOPES
DELAYED RADIATION EFFECTS
DIARRHEA
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
DOSEMETERS
DOSES
ELECTROMAGNETIC RADIATION
ENTERITIS
FEMALE GENITALS
FISTULAE
GAMMA RADIATION
GASTROINTESTINAL TRACT
HEMORRHAGE
IMPLANTS
INTESTINES
IONIZING RADIATIONS
ISODOSE CURVES
ISOTOPES
LARGE INTESTINE
LUMINESCENT DOSEMETERS
MEASURING INSTRUMENTS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
SYMPTOMS
THERAPY
THERMOLUMINESCENT DOSEMETERS
URINARY TRACT
UROGENITAL SYSTEM DISEASES
X RADIATION
YEARS LIVING RADIOISOTOPES