Bladder and rectal complications following radiotherapy for cervix cancer
Journal Article
·
· Gynecol. Oncol.; (United States)
One-hundred and thirty-two patients with cervix carcinoma who were treated with whole pelvis irradiation and two intracavitary applications had bladder and rectal dosimetry during brachytherapy with contrast agents placed into the bladder and rectum prior to orthogonal simulator radiographs. Doses were computer calculated at points A and B, F (bladder), R1 (rectum), and R2 (rectosigmoid). Late occurring bladder and rectal complications were graded on a severity scale of 1 to 3, and 14% had grade 2 or 3 injuries (9% developed fistulas). Statistical evaluation of the data showed that severe bladder and rectal injuries occur more commonly in stage IIIA and IIIB disease and in those receiving high external beam doses (5000 rad +). Analysis of variance tests revealed a significant correlation of brachytherapy dose to points R1 and R2 with severe rectal injuries but there was not a correlation of dose to F with bladder injuries. Nor was there correlation of injuries with dose to point A or the milligram-hour dose. We conclude that our technique for rectal dosimetry is adequate but that an improved technique of bladder dosimetry is needed. Also, when combining whole pelvis irradiation with two intracavitary applications (4000 rad to point A), the whole pelvis dose should probably not exceed 4000-4500 rad.
- Research Organization:
- Hershey Medical Center of the Pennsylvania State Univ. (USA)
- OSTI ID:
- 5297438
- Journal Information:
- Gynecol. Oncol.; (United States), Journal Name: Gynecol. Oncol.; (United States) Vol. 29:1; ISSN GYNOA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Routine clinical estimation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in the treatment of carcinoma of the cervix. [X ray; /sup 137/Cs]
Comparison between DVH-based doses and ICRU point-based doses to the rectum and the bladder using CT-based high-dose rate brachytherapy to the cervix
RECTAL AND BLADDER INJURIES IN RELATION TO RADIATION DOSAGE IN CARCINOMA OF THE CERVIX A 5-YEAR FOLLOW-UP
Conference
·
Fri May 01 00:00:00 EDT 1981
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
·
OSTI ID:6195487
Comparison between DVH-based doses and ICRU point-based doses to the rectum and the bladder using CT-based high-dose rate brachytherapy to the cervix
Journal Article
·
Sat Sep 15 00:00:00 EDT 2018
· Medical Dosimetry
·
OSTI ID:22824205
RECTAL AND BLADDER INJURIES IN RELATION TO RADIATION DOSAGE IN CARCINOMA OF THE CERVIX A 5-YEAR FOLLOW-UP
Journal Article
·
Sat Jul 01 00:00:00 EDT 1961
· American Journal of Obstetrics and Gynecology (U.S.)
·
OSTI ID:4757665
Related Subjects
560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
DIGESTIVE SYSTEM
DISEASES
DOSES
FEMALE GENITALS
GASTROINTESTINAL TRACT
INJURIES
INTESTINES
LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
UTERUS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
DIGESTIVE SYSTEM
DISEASES
DOSES
FEMALE GENITALS
GASTROINTESTINAL TRACT
INJURIES
INTESTINES
LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
UTERUS