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Retinol-binding protein metabolism in liver cells in vivo and in vitro. [Rats]

Journal Article · · Ann. N.Y. Acad. Sci.; (United States)
Immunoreactive retinol-binding proteins (RBP) were isolated and partially characterized from the liver microsomes of normal rats. These studies were undertaken to explore the question of whether microsomal RBP in part represents an intrahepatic precursor that is converted to plasma RBP during the process of secretion. If liver microsomal RBP were significantly composed of a ''pro-RBP'' precursor, then the identification and characterization of the precursor would provide useful information on the molecular events that occur during the process of RBP secretion. These events could then be studied directly, as potential regulatory steps in the overall process of RBP secretion.
Research Organization:
Columbia Univ. College of Physicians and Surgeons, New York, NY
OSTI ID:
6190121
Journal Information:
Ann. N.Y. Acad. Sci.; (United States), Journal Name: Ann. N.Y. Acad. Sci.; (United States) Vol. 359; ISSN ANYAA
Country of Publication:
United States
Language:
English