Effect of quantity and route of administration of manganese monoxide on feed intake and serum manganese in ruminants
The experiment investigated effects of high quantities of manganese and route of administration (diet versus capsule-dosed) on feed intake and blood characteristics in sheep. Twenty-four Florida native or Florida native by St. Croix crossbred wethers, 47 kg initially, were assigned randomly to eight treatments including basal diet supplemented with 0, 3000, 6000, or 9000 ppm manganese as a reagent grade manganese monoxide or basal diet plus gelatin capsules containing the equivalent of 0, 3000, 6000, or 9000 ppm manganese based on intake of the previous day. Three sheep per treatment were provided feed and tap water for ad libitum intake. Sheep were fed basal diet for 7 days followed by a 21-day experimental period, then placed back on the basal diet for 7 days. Average daily feed intake was reduced by increasing supplemental manganese, regardless of route. Animals dosed by capsule consumed less feed than those administered manganese in the diet. Serum manganese increased as manganese supplementation increased, but route of administration had no effect.
- Research Organization:
- Univ. of Florida, Gainesville, FL (United States)
- OSTI ID:
- 6185807
- Journal Information:
- J. Dairy Sci.; (United States), Vol. 68:2
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
FEEDING
INHIBITION
MANGANESE OXIDES
TOXICITY
SHEEP
ANIMAL GROWTH
BLOOD SERUM
DIET
DOSE-RESPONSE RELATIONSHIPS
METABOLISM
ORAL ADMINISTRATION
ANIMALS
CHALCOGENIDES
DOMESTIC ANIMALS
GROWTH
MAMMALS
MANGANESE COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
RUMINANTS
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)