Thorium-229 as an isotopic tracer for the radiochemical determination of thorium isotopes in biological samples
Journal Article
·
· Anal. Chem.; (United States)
The following three advantages make thorium-229 more desirable as an isotopic tracer in biological samples: (1) the increase in accuracy associated with simultaneous ..cap alpha.. spectrometric measurement of the tracer /sup 229/Th and the nuclides being determined /sup 232/ /sup 230/ /sup 228/Th; (2) the long half-life of /sup 229/Th compared with that of /sup 234/Th requires neither the repeated preparation and the associated time-consuming processes of purification and standarization, nor decay corrections; and (3) /sup 229/Th is an ..cap alpha.. emitter as are the isotopes to be determined, and the ..cap alpha.. spectrum provides a measurement of yield. Description of purification of the isotopes, recording of energy spectra, and discussion of /sup 229/Th tracer technique for analysis of Th in human tissue samples are included. (BLM)
- Research Organization:
- New York Univ. Medical Center
- OSTI ID:
- 6169576
- Journal Information:
- Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 50:12; ISSN ANCHA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400103* -- Radiometric & Radiochemical Procedures-- (-1987)
550600 -- Medicine
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ACTINIDES
ALPHA DECAY RADIOISOTOPES
BODY
CHEMICAL ANALYSIS
ELEMENTS
EVEN-ODD NUCLEI
HEAVY NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
METALS
NUCLEI
RADIOCHEMICAL ANALYSIS
RADIOISOTOPES
THORIUM
THORIUM 229
THORIUM ISOTOPES
TISSUES
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES
400103* -- Radiometric & Radiochemical Procedures-- (-1987)
550600 -- Medicine
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ACTINIDES
ALPHA DECAY RADIOISOTOPES
BODY
CHEMICAL ANALYSIS
ELEMENTS
EVEN-ODD NUCLEI
HEAVY NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
METALS
NUCLEI
RADIOCHEMICAL ANALYSIS
RADIOISOTOPES
THORIUM
THORIUM 229
THORIUM ISOTOPES
TISSUES
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES