Chemistry of radiopharmaceuticals

Book · Sun Jan 01 04:00:00 EST 1978

OSTI ID:6168653

Heindel, N D; Burns, H D; Honda, T ^[1]

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1. eds.

The text is a composite of 17 contributions intended to present an overview of the development of radiopharmaceuticals utilizing both chemical and pharmacologic design parameters. Several chapters review the progress of localizing radionuclides in specific tissue on the basis of the organ's physiology and chemistry; several others discuss the chemistry of radiolabeled compounds as a prediction of biologic behavior. The chemistry of technetium is reviewed in one chapter, as are other metals (as one group), and positron emitters in other chapters. The title may be somewhat misleading, however, due to broad topic content. The following are discussed: the role of federal regulatory agencies in radiopharmaceutical development; Brookhaven's contribution to nuclear medicine; and a chapter on the rationale of color imaging. These topics may be pertinent to radiopharmaceutical development, but are somewhat outside the context of chemistry. Each chapter is well referenced. The scope of the text makes it potentially appealing to the physician and the radiopharmaceutical scientist in nuclear medicine. Despite the apparent range of the topics discussed, the necessary brevity of the coverage makes the text possibly useful as either a starting point or as a quick review of parts of radiopharmaceutical science.

• OSTI ID: 6168653
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560171 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL LOCALIZATION
CHEMICAL PREPARATION
CHEMISTRY
DRUGS
ELEMENTS
KINETICS
LABELLED COMPOUNDS
METALS
PARTICLE SOURCES
PATIENTS
PHARMACOLOGY
POSITRON SOURCES
RADIATION SOURCES
RADIOACTIVE MATERIALS
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
REACTION KINETICS
REFRACTORY METALS
SYNTHESIS
TECHNETIUM
TRANSITION ELEMENTS