Arsenic exposure in a copper smelter as related to histological type of lung cancer
Journal Article
·
· Am. J. Ind. Med.; (United States)
Tissue samples from lung cancer patients who had worked at a copper smelter and from controls were collected and classified by a panel of pathologists: 38% of the cancers were found to be adenocarcinomas, compared to 12% among the controls, a statistically significant difference (p less than 0.05). The predominance of adenocarcinomas was associated with arsenic exposure. This finding is not consistent with Kreyberg's hypothesis that small-cell undifferentiated and epidermoid carcinomas are the only type that increase in response to inhaled carcinogens (1962).
- Research Organization:
- Department of Pathology, Tacoma General Hospital, Washington
- OSTI ID:
- 6154381
- Journal Information:
- Am. J. Ind. Med.; (United States), Journal Name: Am. J. Ind. Med.; (United States) Vol. 2:1; ISSN AJIMD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550900 -- Pathology
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ARSENIC
BODY
CARCINOGENS
CARCINOMAS
COPPER
DISEASES
ELEMENTS
HAZARDS
HEALTH HAZARDS
INDUSTRY
LUNGS
METAL INDUSTRY
METALS
NEOPLASMS
OCCUPATIONAL SAFETY
ORGANS
PATHOLOGY
PATIENTS
PERSONNEL
RESPIRATORY SYSTEM
SAFETY
SEMIMETALS
SMELTERS
TRANSITION ELEMENTS
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ARSENIC
BODY
CARCINOGENS
CARCINOMAS
COPPER
DISEASES
ELEMENTS
HAZARDS
HEALTH HAZARDS
INDUSTRY
LUNGS
METAL INDUSTRY
METALS
NEOPLASMS
OCCUPATIONAL SAFETY
ORGANS
PATHOLOGY
PATIENTS
PERSONNEL
RESPIRATORY SYSTEM
SAFETY
SEMIMETALS
SMELTERS
TRANSITION ELEMENTS