Radiobiology of ultrasoft X rays. II. Cultured C3H mouse cells (10T1/2)

Journal Article · Sat Apr 01 04:00:00 EST 1989 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3577424· OSTI ID:6149027

Schillaci, M E; Carpenter, S; Raju, M R; Sebring, R J; Wilder, M E; Goodhead, D T

In the first paper of this series, using V79 cells, we reported that the relative biological effectiveness (RBE) of ultrasoft X rays was found to increase with decreasing energy, and the oxygen enhancement ratio (OER) was found to decrease with decreasing energy. In this report, we present RBE and OER results for 10T1/2 cells that are known to grow uniformly flat and are considerably thinner than V79 cells. Thus the variation in dose across the cell nucleus is considerably reduced. The OER results agree well with our earlier V79 results. However, the RBE values for 10T1/2 cells compared to V79 cells are systematically less for all soft X rays and especially for 0.28 keV carbon-K (1.3 compared to 3.4 for V79 cells). Some plausible explanations are presented to reconcile the apparent discrepancy between V79 and 10T1/2 results.

• Research Organization: Los Alamos National Lab., NM (USA)
• OSTI ID: 6149027
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 118:1; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGY
CELL CULTURES
COMPARATIVE EVALUATIONS
ELECTROMAGNETIC RADIATION
ELEMENTS
IONIZING RADIATIONS
MAMMALS
MICE
NONMETALS
OXYGEN
RADIATIONS
RADIOBIOLOGY
RBE
RODENTS
VERTEBRATES
X RADIATION