Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Histologic review of breast cancer cases in survivors of atomic bombs in Hiroshima and Nagasaki, Japan

Journal Article · · Cancer (Philadelphia); (United States)
; ; ; ; ; ; ; ;
A panel of Japanese and American pathologists reviewed existing histologic material used to study breast cancer risk among the A-bomb survivors in Hiroshima and Nagasaki, a population in which incidence studies have found a strong relationship between breast cancer risk and radiation dose. The primary charge to the panel was to define a body of confirmed cases in the Life Span Study sample of the Radiation Effects Research Foundation that would require little or no review for inclusion in future studies of breast cancer incidence. Broad agreement on histologic type was reached for 298 of 300 confirmed cases. The distribution of histologic types was, overall, similar to that seen in other studies of breast cancer in Japanese women, and did not appear to depend on dose; thus radiation-induced breast cancer appeared to be no different histologically from other breast cancer. Also, no evidence was found of variation in histologic type by city, age at exposure, age at diagnosis, or calendar time.
Research Organization:
Radiation Effects Research Foundation, Hiroshima, Japan
OSTI ID:
6131319
Journal Information:
Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 54:5; ISSN CANCA
Country of Publication:
United States
Language:
English

Similar Records

Radiation-associated lung cancer: A comparison of the histology of lung cancers in uranium miners and survivors of the atomic bombings of Hiroshima and Nagasaki
Journal Article · Sat May 01 00:00:00 EDT 1993 · Radiation Research; (United States) · OSTI ID:6385426
Malignant breast tumors among Atomic Bomb Survivors, Hirsoshima and Nagasaki, 1950 to 1974
Journal Article · Fri Jun 01 00:00:00 EDT 1979 · J. Natl. Cancer Inst.; (United States) · OSTI ID:6000398
LEUKEMIA IN NAGASAKI ATOMIC BOMB SURVIVORS FROM 1945 THROUGH 1959
Journal Article · Sun Dec 31 23:00:00 EST 1961 · Bulletin of the World Health Organization (U.S.) · OSTI ID:4772645

Related Subjects

560151* -- Radiation Effects on Animals-- Man
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
A-BOMB SURVIVORS
AGE DEPENDENCE
ASIA
BODY
CARCINOMAS
DISEASES
DOCUMENT TYPES
DOSES
GLANDS
HIROSHIMA
HISTOLOGY
HUMAN POPULATIONS
JAPAN
MAMMARY GLANDS
NAGASAKI
NEOPLASMS
ORGANS
PATIENTS
POPULATIONS
RADIATION DOSES
RADIOINDUCTION
REVIEWS
RISK ASSESSMENT