Pathologic effects in rodents exposed to sodium combustion products
Journal Article
·
· Environ. Res.; (United States)
Three species of rodents exhibited respiratory distress when exposed to aerosols of sodium combustion products, the major constituent of which was shown to be sodium carbonate. At the higher doses, animals died during or shortly after 2 hr exposures. Lesions, primarily involving the pharynx and larynx, included accumulation of mucus, vesiculation, and mucosal edema. Other lesions included edema and vesiculation of the anterior trachea, hemorrhage in the lungs, and severe gastric tympany. Basal epithelial cells of the posterior pharynx and anterior trachea had enlarged mitochondria following exposures of 1 hr or more.
- Research Organization:
- Pacific Northwest Lab., Richland, WA
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 6129144
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 31; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ALKALI METAL COMPOUNDS
ALKALI METALS
ANIMALS
CARBON COMPOUNDS
CARBONATES
COLLOIDS
COMBUSTION PRODUCTS
DISPERSIONS
ELEMENTS
GUINEA PIGS
INJURIES
MAMMALS
METALS
MICE
MORTALITY
OXYGEN COMPOUNDS
RATS
RESPIRATORY SYSTEM
RODENTS
SODIUM
SODIUM CARBONATES
SODIUM COMPOUNDS
SOLS
TOXICITY
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ALKALI METAL COMPOUNDS
ALKALI METALS
ANIMALS
CARBON COMPOUNDS
CARBONATES
COLLOIDS
COMBUSTION PRODUCTS
DISPERSIONS
ELEMENTS
GUINEA PIGS
INJURIES
MAMMALS
METALS
MICE
MORTALITY
OXYGEN COMPOUNDS
RATS
RESPIRATORY SYSTEM
RODENTS
SODIUM
SODIUM CARBONATES
SODIUM COMPOUNDS
SOLS
TOXICITY
VERTEBRATES