Prediction of retention times in serially linked open-tubular gas chromatographic columns and optimization of column lengths

Journal Article · Thu Nov 01 00:00:00 EST 1990 · Analytical Chemistry (Washington); (USA)

DOI:https://doi.org/10.1021/ac00220a009· OSTI ID:6108742

Jones, J R; Purnell, J H ^[1]

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1. Univ. College of Swansea, Wales (England)

The serial gas chromatographic theory, first advanced and then further developed by Purnell and Williams, is used to optimize the analysis of a nine-component phenol mixture by use of linked capillary columns. The capacity factors of sample components with the system serially coupled in either mode, column A/column B or column B/column A, and of different relative length, are shown to agree essentially exactly with those predicted by theory. The window analysis procedure devised by Laub and Purnell is then used to calculate the relative and overall length of the columns required to achieve base-line resolution. The experimental chromatograms are shown to correspond precisely to prediction. When the methodology is applied generally, it is shown that the requisite data can be determined easily and rapidly and the subsequent calculations can be carried out via an equally simple computer program. The consequent techniques are procedures should help the development of serial-coupled open-tubular column chromatography (SCOTCH).

• OSTI ID: 6108742
• Journal Information: Analytical Chemistry (Washington); (USA), Vol. 62:21; ISSN 0003-2700
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
GAS CHROMATOGRAPHY
EXTRACTION COLUMNS
PHENOL
CALCULATION METHODS
EXPERIMENTAL DATA
MEASURING METHODS
RETENTION FUNCTIONS
THEORETICAL DATA
AROMATICS
CHROMATOGRAPHY
DATA
EXTRACTION APPARATUSES
FUNCTIONS
HYDROXY COMPOUNDS
INFORMATION
NUMERICAL DATA
ORGANIC COMPOUNDS
PHENOLS
SEPARATION EQUIPMENT
SEPARATION PROCESSES
400102* - Chemical & Spectral Procedures