Obstructive ureteropathy following radiation therapy for carcinoma of the cervix

Journal Article · Mon May 01 00:00:00 EDT 1989 · Gynecol. Oncol.; (United States)

DOI:https://doi.org/10.1016/0090-8258(89)90559-3· OSTI ID:6097353

Parliament, M; Genest, P; Girard, A; Gerig, L; Prefontaine, M

Between January 1959 and December 1986, 10 of 328 patients (3%) treated with curative intent using primary radiation therapy for carcinoma of the cervix developed obstructive ureteropathy due to fibrosis. The mean age of the patients with obstructive ureteropathy was 45 years and the median time to obstruction was 26 months. The obstruction was unilateral in 8 cases and involved the parametrial portion of the ureter in at least 5 cases. No predisposing risk factor was found to be associated with the development of obstructive ureteropathy. After corrective surgery, renal function remained normal in 8 patients, and resolution of the hydronephrosis occurred in 4 patients.

• Research Organization: Ottawa General Hospital Division (Canada)
• OSTI ID: 6097353
• Journal Information: Gynecol. Oncol.; (United States), Journal Name: Gynecol. Oncol.; (United States) Vol. 33:2; ISSN GYNOA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARCINOMAS
DISEASES
FEMALE GENITALS
FEMALES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
UROGENITAL SYSTEM DISEASES
UTERUS