Recurrence of posterior uveal melanoma after /sup 60/Co episcleral plaque therapy
Journal Article
·
· Ophthalmology (Rochester, Minn.); (United States)
The authors analyzed the clinical and follow-up data on 277 selected patients with primary choroidal or ciliochoroidal melanoma who were treated with /sup 60/Co plaque radiotherapy between 1976 and 1982. Local recurrence of the irradiated melanoma developed in 39 (14%) patients during the follow-up interval. The 5-year tumor recurrence rate (Kaplan-Meier) was estimated to be 12%. Multivariate prognostic factor analysis (Cox proportional hazards modeling) identified the largest linear tumor dimension and proximity of the posterior margin of the tumor to the optic nerve head as predictors of recurrence. The 5-year survival rate of patients whose tumors recurred (58%) was significantly (log-rank test P = 0.0023) worse than that of patients whose tumor remained clinically controlled (82%).
- Research Organization:
- Hahnemann Univ. School of Medicine, Philadelphia, PA (USA)
- OSTI ID:
- 6070859
- Journal Information:
- Ophthalmology (Rochester, Minn.); (United States), Journal Name: Ophthalmology (Rochester, Minn.); (United States) Vol. 96:3; ISSN OPHTD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
COBALT 60
COBALT ISOTOPES
DISEASES
EYES
FACE
HEAD
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATHEMATICS
MEDICINE
MELANOMAS
MINUTES LIVING RADIOISOTOPES
MULTIVARIATE ANALYSIS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SENSE ORGANS
STATISTICS
SURVIVAL CURVES
THERAPY
UVEA
YEARS LIVING RADIOISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
COBALT 60
COBALT ISOTOPES
DISEASES
EYES
FACE
HEAD
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATHEMATICS
MEDICINE
MELANOMAS
MINUTES LIVING RADIOISOTOPES
MULTIVARIATE ANALYSIS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SENSE ORGANS
STATISTICS
SURVIVAL CURVES
THERAPY
UVEA
YEARS LIVING RADIOISOTOPES