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Catalytic conversion of. beta. -hydroxy carboxylic acids to olefins by tungsten(V) complexes: A new acyl group transfer catalyst

Journal Article · · Organometallics; (United States)
DOI:https://doi.org/10.1021/om00162a010· OSTI ID:6070333
;  [1]
  1. Princeton Univ., NJ (United States)

Oxotungsten tetrachloride catalyzes the conversion of {beta}-hydroxy carboxylic acids to olefins, in the presence of base. The reaction proceeds in high yield, stereospecifically, and with high catalyst turnover. Examination of the likely stoichiometric steps for {beta}-hydroxy carboxylic acid activation shows the formation of intermediate chelates, structures of which were studied by {sup 1}H NMR. The role of the base was probed by using both {sup 1}H and {sup 183}W NMR, and it was shown that base simply deprotonates the chelate; base does not coordinate to the W center. {beta}-Lactones were the initial products of this sequence from which decarboxylation occurred to give the olefinic product.

OSTI ID:
6070333
Journal Information:
Organometallics; (United States), Journal Name: Organometallics; (United States) Vol. 9:12; ISSN 0276-7333; ISSN ORGND
Country of Publication:
United States
Language:
English