Radiofrequency radiation-induced calcium ion efflux enhancement from human and other neuroblastoma cells in culture

Journal Article · Sun Jan 01 04:00:00 EST 1989 · Bioelectromagnetics (N.Y.); (United States)

DOI:https://doi.org/10.1002/bem.2250100208· OSTI ID:6070070

Dutta, S K; Ghosh, B; Blackman, C F

To test the generality of radiofrequency radiation-induced changes in /sup 45/Ca2+ efflux from avian and feline brain tissues, human neuroblastoma cells were exposed to electromagnetic radiation at 147 MHz, amplitude-modulated (AM) at 16 Hz, at specific absorption rates (SAR) of 0.1, 0.05, 0.01, 0.005, 0.001, and 0.0005 W/kg. Significant /sup 45/Ca2+ efflux was obtained at SAR values of 0.05 and 0.005 W/kg. Enhanced efflux at 0.05 W/kg peaked at the 13-16 Hz and at the 57.5-60 Hz modulation ranges. A Chinese hamster-mouse hybrid neuroblastoma was also shown to exhibit enhanced radiation-induced /sup 45/Ca2+ efflux at an SAR of 0.05 W/kg, using 147 MHz, AM at 16 Hz. These results confirm that amplitude-modulated radiofrequency radiation can induce responses in cells of nervous tissue origin from widely different animal species, including humans. The results are also consistent with the reports of similar findings in avian and feline brain tissues and indicate the general nature of the phenomenon.

• Research Organization: Howard Univ., Washington, DC (USA)
• OSTI ID: 6070070
• Journal Information: Bioelectromagnetics (N.Y.); (United States), Journal Name: Bioelectromagnetics (N.Y.); (United States) Vol. 10:2; ISSN BLCTD
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ALKALINE EARTH METAL COMPOUNDS
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIRDS
BODY
BRAIN
CALCIUM 45
CALCIUM COMPOUNDS
CALCIUM ISOTOPES
CATS
CENTRAL NERVOUS SYSTEM
DAYS LIVING RADIOISOTOPES
ELECTROMAGNETIC RADIATION
EVEN-ODD NUCLEI
FREQUENCY RANGE
HAMSTERS
HZ RANGE
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MAN
MHZ RANGE
MHZ RANGE 100-1000
NERVE CELLS
NERVOUS SYSTEM
NUCLEI
ORGANS
PRIMATES
RADIATIONS
RADIOISOTOPES
RADIOWAVE RADIATION
RODENTS
SECRETION
SOMATIC CELLS
TRACER TECHNIQUES
TUMOR CELLS
VERTEBRATES