Effect of dietray cadmium on tissue distribution of /sup 109/cadmium following a single oral dose in young goats

Journal Article · Wed Jan 01 00:00:00 EST 1969 · J. Dairy Sci.; (United States)

DOI:https://doi.org/10.3168/jds.S0022-0302(69)86891-8· OSTI ID:6062110

Miller, W J; Blackmon, D M; Gentry, R P; Pate, F M

Cadmium metabolism was investigated following a single oral dose of /sup 109/Cd in four- to six-month-old male goats fed a practical diet with and without 100 ppm of supplemental cadmium as CdCl/sub 2/. Highest concentrations were found in the kidneys, liver, duodenum, and abomasum, respectively. Bone, muscle, blood, hair, skin, and connective tissues contained very small amounts. Feeding the high metabolic load of 100 ppm of dietary cadmium significantly decreased /sup 109/Cd concentrations in the gastrointestinal tract tissues, but the effect was not sufficient to produce a detectable change in over-all body retention. /sup 109/Cadmium levels in other tissues were not materially influenced by cadmium feeding. Daily rate of /sup 109/Cd fecal excretion declined linearly and rapidly during the second week, with about 20% of the body burden eliminated on Day 8 and less than 5% on Day 14. Ruminants do not have a homeostatic control mechanism for controlling cadmium absorption or excretion which is affected by level of dietary or tissue cadmium content. However, very low levels are absorbed. 21 references, 2 figures, 4 tables.

• Research Organization: Univ. of Georgia, Athens, GA (United States)
• OSTI ID: 6062110
• Journal Information: J. Dairy Sci.; (United States), Vol. 52
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
54 ENVIRONMENTAL SCIENCES
CADMIUM
EXCRETION
INTESTINAL ABSORPTION
TISSUE DISTRIBUTION
BLOOD
BONE TISSUES
CADMIUM 109
CADMIUM CHLORIDES
GASTROINTESTINAL TRACT
GOATS
HAIR
INGESTION
KIDNEYS
LIVER
METABOLISM
MUSCLES
SKIN
TRACER TECHNIQUES
ABSORPTION
ANIMAL TISSUES
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CADMIUM COMPOUNDS
CADMIUM HALIDES
CADMIUM ISOTOPES
CHLORIDES
CHLORINE COMPOUNDS
CLEARANCE
CONNECTIVE TISSUE
DIGESTIVE SYSTEM
DISTRIBUTION
DOMESTIC ANIMALS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
GLANDS
HALIDES
HALOGEN COMPOUNDS
INTAKE
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MATERIALS
METALS
NUCLEI
ORGANS
RADIOISOTOPES
RUMINANTS
TISSUES
UPTAKE
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
510200 - Environment
Terrestrial- Chemicals Monitoring & Transport- (-1989)