Reactor beam calculations to determine optimum delivery of epithermal neutrons for treatment of brain tumors
Conference
·
OSTI ID:604362
- Idaho National Engineering & Environmental Lab., Idaho Falls, ID (United States)
- Brookhaven National Lab., Upton, NY (United States); and others
Studies were performed to assess theoretical tumor control probability (TCP) for brain-tumor treatment with boron neutron capture therapy (BNCT) using epithermal neutron sources from reactors. The existing epithermal-neutron beams at the Brookhaven Medical Research Reactor Facility (BMRR), the Petten High Flux Reactor Facility (HWR) and the Finnish Research Reactor 1 (FIR1) have been analyzed and characterized using common analytical and measurement methods allowing for this inter-comparison. Each of these three facilities is unique and each offers an advantage in some aspect of BNCT, but none of these existing facilities excel in all neutron-beam attributes as related to BNCT. A comparison is therefore also shown for a near-optimum reactor beam which does not currently exist but which would be feasible with existing technology. This hypothetical beam is designated BNCT-1 and has a spectrum similar to the FIR-1, the mono-directionality of the HFR and the intensity of the BMRR. A beam very similar to the BNCT-1 could perhaps be achieved with modification of the BMRR, HFR, or FIR, and could certainly be realized in a new facility with today`s technology.
- Research Organization:
- Idaho National Engineering Lab., Idaho Falls, ID (United States)
- Sponsoring Organization:
- USDOE Office of Energy Research, Washington, DC (United States)
- DOE Contract Number:
- AC07-94ID13223
- OSTI ID:
- 604362
- Report Number(s):
- INEL/CON--97-00694; CONF-971125--; ON: DE98050462
- Country of Publication:
- United States
- Language:
- English
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