Radiation management of carcinoma of the cervical stump. [Complications following external and internal radiotherapy]
In spite of a low incidence of carcinoma of the cervical stump at the present time, the management of this interesting disease deserves special attention because of the success which can be obtained with proper treatment. Of 107 cases treated, only 100 cases were true cases of carcinoma of the stump and were eligible for this study. 7 cases were excluded from the study because they were probably coincidental carcinomas and were treated soon after subtotal hysterectomy. The lesions were staged according to the FIGO system. 93 cases were invasive squamous cell carcinoma, 6 cases adenocarcinoma and 1 case transitional cell carcinoma. Of 100 cases with a minimum 5 year follow-up, the absolute 5-year cure rate for various clinical stages is as follows: State I 83.3% (20/24); Stage IIA 75.0% (9/12); Stage IIB 62.5% (20/32); Stage IIIA 50% (1/2); Stage IIIB 48% (12/25); Stage IV 20% (1/5). The overall absolute 5-year cure rate for all stages combined is 63%. A better result in Stage IIIB as compared to several previous reports is thought to be due to extensive and aggressive interstitial radium therapy properly combined with external supervoltage irradiation. Techniques of treatment stage by stage including computerized dosimetry are discussed along with complications and failures.
- Research Organization:
- Univ. of Maryland Hospital, Baltimore
- OSTI ID:
- 6036918
- Journal Information:
- Cancer; (United States), Vol. 43:4; Conference: 20. annual meeting of the American Society of Therapeutic Radiologists, Los Angelas, CA, USA, 31 Oct 1978
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BLADDER
DELAYED RADIATION EFFECTS
FEMALE GENITALS
FISTULAE
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
RECTUM
BETATRONS
CARCINOMAS
COBALT 60
EXTERNAL IRRADIATION
FRACTIONATED IRRADIATION
GAMMA RADIATION
INTERNAL IRRADIATION
LINEAR ACCELERATORS
PARTIAL BODY IRRADIATION
PATIENTS
PELVIS
RADIATION SOURCE IMPLANTS
RADIUM
UTERUS
WOMEN
X RADIATION
ACCELERATORS
ALKALINE EARTH METALS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
COBALT ISOTOPES
CYCLIC ACCELERATORS
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTS
FEMALES
GASTROINTESTINAL TRACT
IMPLANTS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
INTESTINES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARGE INTESTINE
MAMMALS
MAN
MEDICINE
METALS
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
RADIATION EFFECTS
RADIATION SOURCES
RADIATIONS
RADIOISOTOPES
RADIOLOGY
THERAPY
URINARY TRACT
VERTEBRATES
YEARS LIVING RADIOISOTOPES
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550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)