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Regiospecific synthesis of 2-substituted 4-methyl-3,6-dihydro-2h-pyrans

Journal Article · · Chem. Heterocycl. Compd. (Engl. Transl.); (United States)
OSTI ID:6033917

The chloroalkylation of 3-halo-2-methyl-1-buten-4-ols was used to synthesize 4,5-dihalo-4-methyl-2-substituted tetrahydropyrans, which were converted regio-specifically to 3,6-dihydropyrans by reaction with magnesium. A similar reaction with zinc dust gave mixtures of 3,6- and 5,6-dihydropyrans.

Research Organization:
Institute of Organic Chemistry, Yerevan, USSR
OSTI ID:
6033917
Journal Information:
Chem. Heterocycl. Compd. (Engl. Transl.); (United States), Journal Name: Chem. Heterocycl. Compd. (Engl. Transl.); (United States) Vol. 21:9; ISSN CHCCA
Country of Publication:
United States
Language:
English