No activation of new initiation points for deoxyribonucleic acid replication in BALB/c 3T3 cells transformed by Kirsten sarcoma virus
Journal Article
·
· Mol. Cell. Biol.; (United States)
BALB/c 3T3 cells were transformed by Kirsten sarcoma virus, and five clones were isolated in soft agar. Average replicon sizes of the transformed cell lines were stimated by the method of fiber-autoradiography and found to be the same size as the nontransformed 3T3 cells, analyzed in parallel. The results indicate that, unlike simian virus 40 and Epstein-Barr virus, Kirsten sarcoma virus does not activate new initiation points for cellular deoxyribonucleic acid replication in murine sarcome virus-transformed BALB/c 3T3 cells.
- Research Organization:
- National Cancer Institute, Bethesda, MD 20205
- OSTI ID:
- 6030320
- Journal Information:
- Mol. Cell. Biol.; (United States), Journal Name: Mol. Cell. Biol.; (United States) Vol. 1:8; ISSN MCEBD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550201* -- Biochemistry-- Tracer Techniques
550401 -- Genetics-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AGAR
ANIMAL CELLS
AUTORADIOGRAPHY
BIOLOGICAL FUNCTIONS
CARBOHYDRATES
CELL TRANSFORMATIONS
COLLOIDS
CULTURE MEDIA
DISEASES
DISPERSIONS
DNA REPLICATION
FUNCTIONS
GENES
MICROORGANISMS
MOLECULAR BIOLOGY
NEOPLASMS
NUCLEIC ACID REPLICATION
ONCOGENIC VIRUSES
ORGANIC COMPOUNDS
PARASITES
POLYSACCHARIDES
REPLICONS
SACCHARIDES
SARCOMAS
SIMIAN VIRUS
SIZE
VIRUSES
550401 -- Genetics-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AGAR
ANIMAL CELLS
AUTORADIOGRAPHY
BIOLOGICAL FUNCTIONS
CARBOHYDRATES
CELL TRANSFORMATIONS
COLLOIDS
CULTURE MEDIA
DISEASES
DISPERSIONS
DNA REPLICATION
FUNCTIONS
GENES
MICROORGANISMS
MOLECULAR BIOLOGY
NEOPLASMS
NUCLEIC ACID REPLICATION
ONCOGENIC VIRUSES
ORGANIC COMPOUNDS
PARASITES
POLYSACCHARIDES
REPLICONS
SACCHARIDES
SARCOMAS
SIMIAN VIRUS
SIZE
VIRUSES