Regional cerebral blood flow and anxiety: a correlation study in neurologically normal patients

Journal Article · Thu Jun 01 04:00:00 EDT 1989 · J. Cereb. Blood Flow Metab.; (United States)

DOI:https://doi.org/10.1038/jcbfm.1989.60· OSTI ID:6025056

Rodriguez, G; Cogorno, P; Gris, A; Marenco, S; Mesiti, C; Nobili, F; Rosadini, G

Regional CBF (rCBF) was evaluated by the /sup 133/Xe inhalation method in 60 neurologically normal patients (30 men and 30 women) and hemispheric and regional values were correlated with anxiety measurements collected by a self-rating questionnaire before and after the examination. Statistically significant negative correlations between rCBF and anxiety measures were found. rCBF reduction for high anxiety levels is in line with results previously reported by others and could be related to lower performance levels for moderately high anxiety scores as those reported in the present population. This could perhaps be explained by rearrangement of flow from cortical zones to deeper areas of the brain, classically known to be implicated in the control of emotions. However, these results should be interpreted cautiously, since they were obtained in patients and not in normal subjects.

• Research Organization: Univ. of Genova (Italy)
• OSTI ID: 6025056
• Journal Information: J. Cereb. Blood Flow Metab.; (United States), Journal Name: J. Cereb. Blood Flow Metab.; (United States) Vol. 9:3; ISSN JCBMD
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
BETA DECAY RADIOISOTOPES
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BLOOD FLOW
BODY
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