A very convenient synthesis of cyclopenta(cd)pyrene
Journal Article
·
· Journal of Organic Chemistry; (United States)
- Leiden Univ. (Netherlands)
Cyclopenta(cd)pyrene (CPP, 5), a constituent of the class of the polycyclic aromatic hydrocarbons, occurs in a wide variety of carbon black soots, in cigarette smoke, and in car engine exhaust gases. CPP has been shown to be a potent bacterial mutagen, and it is carcinogenic on the skin and in the lungs of mice. Studies on the biological activity and metabolism of CPP and its derivatives require relatively large amounts of CPP. The authors have developed a photochemical route which is very suitable for small scale production of CPP and can also be very useful in the synthesis of substituted CPPs because it uses standard laboratory procedures and is cheap, efficient, and safe.
- OSTI ID:
- 6013136
- Journal Information:
- Journal of Organic Chemistry; (United States), Journal Name: Journal of Organic Chemistry; (United States) Vol. 55:2; ISSN JOCEA; ISSN 0022-3263
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BIOLOGICAL EFFECTS
CARBON
CARBON BLACK
CHEMICAL PREPARATION
CONDENSED AROMATICS
ELEMENTS
EXHAUST GASES
EXPERIMENT PLANNING
FLUIDS
GASEOUS WASTES
GASES
HYDROCARBONS
METABOLISM
NONMETALS
ORGANIC COMPOUNDS
PLANNING
POLYCYCLIC AROMATIC HYDROCARBONS
PYRENE
SOOT
SYNTHESIS
TOBACCO PRODUCTS
WASTES
400201* -- Chemical & Physicochemical Properties
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BIOLOGICAL EFFECTS
CARBON
CARBON BLACK
CHEMICAL PREPARATION
CONDENSED AROMATICS
ELEMENTS
EXHAUST GASES
EXPERIMENT PLANNING
FLUIDS
GASEOUS WASTES
GASES
HYDROCARBONS
METABOLISM
NONMETALS
ORGANIC COMPOUNDS
PLANNING
POLYCYCLIC AROMATIC HYDROCARBONS
PYRENE
SOOT
SYNTHESIS
TOBACCO PRODUCTS
WASTES