Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Urinary delta-aminolevulinic acid (ALA) excretion in humans and cattle as an index of exposure to lead

Journal Article · · Vet. Hum. Toxicol.; (United States)
OSTI ID:6010386
;

Disposable ion-exchange chromatographic columns were used to determine delta-aminolevulinic acid (ALA) concentrations in 11 bovine and 184 human urine samples. The mean urinary ALA concentrations in persons working as battery chargers, autopainters, automechanics, and urban first-grade pupils were 11.61 +/- 14.23, 6.51 +/- 3.31, 6.48 +/- 3.36, and 5.71 +/- 2.91 micrograms/ml respectively. These values were higher than those found in urine from gasoline station attendants, university students and laboratory assistants, rural adult farmers, and rural first-grade pupils, which were 4.90 +/- 1.95, 4.93 +/- 1.76, 4.40 +/- 1.79 and 4.51 +/- 2.65 micrograms/ml respectively. In cattle (Holstein Friesian/White Fulani cross) the mean urinary ALA concentration was 1.84 +/- 0.04 micron/ml. The data indicates that persons working around automobile, lead batteries and leaded gasoline had elevated ALA concentrations in urine. Rural humans and cattle did not have significant elevations of urinary ALA.

OSTI ID:
6010386
Journal Information:
Vet. Hum. Toxicol.; (United States), Journal Name: Vet. Hum. Toxicol.; (United States) Vol. 22:6; ISSN VHTOD
Country of Publication:
United States
Language:
English

Similar Records

Optimized fluorometric determination of urinary delta-aminolevulinic acid by using pre-column derivatization, and identification of the derivative
Journal Article · Wed Aug 01 00:00:00 EDT 1990 · Clinical Chemistry (Winston-Salem, North Carolina); (USA) · OSTI ID:6788515
Absorption and excretion of mercury in man. XIII. Effects of mercury exposure on urinary excretion of coproporphyrin and delta-aminolevulinic acid
Journal Article · Fri Sep 01 00:00:00 EDT 1967 · Arch. Environ. Health; (United States) · OSTI ID:6402933
Measurement of urinary histamine: comparison of fluorometric and radioisotopic-enzymatic assay procedures
Journal Article · Sun Jan 31 23:00:00 EST 1982 · J. Allergy Clin. Immunol.; (United States) · OSTI ID:5996357

Related Subjects

560305 -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADULTS
AGE GROUPS
AMINO ACIDS
AMINOLEVULINIC ACID
ANIMALS
BIOLOGICAL INDICATORS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CARBOXYLIC ACIDS
CATTLE
CHILDREN
CHROMATOGRAPHY
CLEARANCE
COMMERCIAL SECTOR
DOMESTIC ANIMALS
ELECTRIC BATTERIES
ELECTROCHEMICAL CELLS
ELEMENTS
EXCRETION
GASOLINE SERVICE STATIONS
HUMAN POPULATIONS
ION EXCHANGE CHROMATOGRAPHY
LEAD
LEAD-ACID BATTERIES
MAMMALS
MAN
MARKETERS
MATERIALS
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
PERSONNEL
POPULATIONS
PRIMATES
RETAILERS
RUMINANTS
RURAL AREAS
SEPARATION PROCESSES
URBAN AREAS
URINE
VERTEBRATES
WASTES