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Reduction of 2-vinyl-1,1-bis(bromomethyl)cyclopropane

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:6007627

A study was carried out on the reduction of 2-vinyl-1,1-bis(bromomethyl)cyclopropane by various methods including electrochemical procedures. The major reaction pathways entail opening and expansion of the cyclopropane ring, while the product of the formation of a second three-membered ring, namely, vinylspiropentane, is formed in low yield. The probable radical mechanism for this reaction is discussed. Alkylation of diethyl malonate by trans-1,4-dibromo-2-butene using potassium carbonate as the base in absolute ethanol leads to the formation of diester in 63% yield. The use of the K/sub 2/CO/sub 3/-DMSO system, in contrast to the authors previous results, leads to the formation of desired product in yields from 5 to 10%. The reduction of diester by lithium aluminum hydride in ether gives 2-vinyl-1,1-bis(hydroxymethyl)cyclopropane in 84% yield.

Research Organization:
M.V. Lomonosov Moscow State Univ. (USSR)
OSTI ID:
6007627
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 23:10; ISSN JOCYA
Country of Publication:
United States
Language:
English

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