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Problems of molecular design and the computer. XII. A computer search for possible intermediates in the reduction of 2-vinyl-1,1-bis(bromomethyl)cyclopropane using the FLAMINGO program system

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:5949665

A description has been given for the previously developed FLAMINGO computer system for the prediction of the mechanisms of complex organic reactions in the case of the reduction of 2-vinyl-1,1-bis(bromomethyl)cyclopropane. The operation of the program and the criteria for sorting the results generated by the computer were given. Operation of the program gave the structures of all possible intermediates and reaction products taking account of previously indicated limitations. All the computer predictions of the transformations were analyzed from the viewpoint of the chemistry of this reaction. The results of the computer search indicated the mixed anionic and radical mechanism of this reaction and gave the possible pathways for the formation of each compound obtained in an experimental study of this reaction.

Research Organization:
M.V. Lomonosov Moscow State Univ. (USSR)
OSTI ID:
5949665
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 24:1; ISSN JOCYA
Country of Publication:
United States
Language:
English