Postoperative radionuclide evaluation of osteoid osteomas

Journal Article · Tue Feb 01 04:00:00 EST 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.146.2.6217488· OSTI ID:5997937

Ghelman, B; Vigorita, V J

Five cases of clinically suspected osteoid osteomas were studied by preoperative injection of technetium-99m methylene disphosphonate, intraoperative localization with a radiation-sensitive scintillation probe, and postoperative examination of the entire tissue specimen (including the presumed nidus and surrounding bone). Microradiography and light microscopy were also used. In addition, a new autoradiography technique was introduced in which the excised surgical specimen was placed on undeveloped x-ray film for pathologic localization, diagnosis of the lesions, and a study of the relative intensity of radioactive uptake in the nidus vs. surrounding bone. Autoradiography revealed that the nidus showed the greatest concentration of radioactivity, followed by the surrounding bone. The authors conclude that /sup 99m/Tc can be used clinically in localizing osteoid osteomas and that preoperative and intraoperative scanning can assist in conservative surgical excision. For small lesions, autoradiography assists the pathologist in identifying an osteoid osteoma.

• Research Organization: Department of Radiology, Cornell University Medical College, New York
• OSTI ID: 5997937
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 146:2; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMAL TISSUES
AUTORADIOGRAPHY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL LOCALIZATION
BODY
BONE TISSUES
COMPARATIVE EVALUATIONS
CONNECTIVE TISSUE
DIAGNOSIS
DIAGNOSTIC USES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NORTH AMERICA
NUCLEI
ODD-EVEN NUCLEI
OSTEOSARCOMAS
PATIENTS
RADIOISOTOPES
SARCOMAS
SKELETAL DISEASES
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
USA
USES
YEARS LIVING RADIOISOTOPES