Postoperative radionuclide evaluation of osteoid osteomas

Journal Article · Tue Feb 01 00:00:00 EST 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.146.2.6217488· OSTI ID:5917011

Ghelman, B; Vigorita, V J

Five cases of clinically suspected osteoid osteomas were studied by preoperative injectin of technetium-99m methylene disphosphonate, intraoperative localization with a radiation-sensitive scintillation probe, and postoperative examination of the entire tissue specimen (including the presumed nidus and surrounding bone). Microradiography and light microscopy were also used. In addition, a new autoradiography technique was introduced in which the excised surgical specimen was placed on undeveloped x-ray film for pathologic localizaton, diagnosis of the lesions, and a study of the relative intensity of radioactive uptake in the nidus vs. surrounding bone. Autoradiography revealed that the nidus showed the greatest concentration of radioactivity, followed by the surrounding bone. The authors conclude that lt. slashsup 99mlt. slashTc can be used clinically in localizing osteoid osteomas and that preoperative and intraoperative scanning can assist in conservative surgical excision, e.g., minimal extirpation of bone in delicate areas such as the spine. For small lesions, autoradiography assists the pathologist in identifying an osteoid osteoma.

• Research Organization: Cornell Univ. Medical Coll., New York, NY
• OSTI ID: 5917011
• Journal Information: Radiology; (United States), Vol. 146:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
NEOPLASMS
BIOLOGICAL LOCALIZATION
SKELETON
SCINTISCANNING
TECHNETIUM 99
AUTORADIOGRAPHY
ISOMERIC NUCLEI
PATIENTS
PHOSPHONATES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics