Determination of left-ventricular volume from first-pass kinetics of labeled red cells

Journal Article · Tue Feb 01 04:00:00 EST 1983 · J. Nucl. Med.; (United States)

OSTI ID:5997589

Harpen, M D; Dubuisson, R L; Head, G B; Parmley, L F; Jones, T B; Robinson, A E

A mathematical model is presented for the dynamics of a bolus of /sup 99m/Tc labeled red blood cells through the left ventricle. It is used to correct for attenuation the count rate observed over the left ventricle during a conventional gated blood-pool study. The left-ventricular volumes are calculated from the corrected count rates and expressed as a percentage of total blood volume, or in absolute terms if a blood sample is obtained. The procedure is applied to a number of patients with nonvalvular cardiac disease. Cardiac volumes determined by the method are found to correlate well (r . 0.98) with those determined by contrast left ventriculography. The method is simple, requires no special equipment, and can be applied with existing computer software.

• Research Organization: University of South Alabama Medical Center, Mobile
• OSTI ID: 5997589
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 24:2; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BIOMEDICAL RADIOGRAPHY
BLOOD
BLOOD CELLS
BLOOD CIRCULATION
BODY
BODY FLUIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ERYTHROCYTES
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MATHEMATICAL MODELS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGY
RADIOISOTOPES
RADIOLOGY
TECHNETIUM 99
TECHNETIUM ISOTOPES
USES
VOLUME
YEARS LIVING RADIOISOTOPES