Left ventricular performance during exercise in patients with left bundle branch block: evaluation by gated radionuclide ventriculography

Journal Article · Sat Jan 01 04:00:00 EST 1983 · Am. Heart J.; (United States)

DOI:https://doi.org/10.1016/0002-8703(83)90280-6· OSTI ID:5997195

Rowe, D W; De Puey, E G; Sonnemaker, R E; Hall, R J; Burdine, J A

To investigate changes in left ventricular (LV) function during exercise in patients with left bundle branch block (LBBB), 22 patients without a history or physical findings of previous myocardial infarction or LV dysfunction were studied by gated radionuclide ventriculography (GRNV) at rest and during bicycle exercise. Coronary arteriography demonstrated greater than 75% diameter narrowing of at least one coronary artery in nine patients. Of the remaining 13 patients, GRNV demonstrated wall motion abnormalities in seven patients either at rest or with exercise. During exercise, mean ejection fraction (EF) did not increase in patients without coronary artery disease (CAD). Patients with CAD had a 12-point fall in mean EF with exercise. Researchers conclude that LV reserve, as demonstrated by ability to increase EF with exercise, is impaired in patients with LBBB even in the absence of CAD or other underlying cardiac disease and that standard GRNV criteria to exclude the presence of CAD (a greater than five-point increase in EF with exercise and normal wall motion) are not strictly applicable in screening patients with LBBB.

• Research Organization: Section of Cardiology, St. Luke's Episcopal Hospital, Fresno, CA
• OSTI ID: 5997195
• Journal Information: Am. Heart J.; (United States), Journal Name: Am. Heart J.; (United States) Vol. 105:1; ISSN AHJOA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD PRESSURE
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CORONARIES
DIAGNOSTIC USES
DISEASES
DYNAMIC FUNCTION STUDIES
EXERCISE
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MYOCARDIAL INFARCTION
NORTH AMERICA
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
TECHNETIUM 99
TECHNETIUM ISOTOPES
USA
USES
YEARS LIVING RADIOISOTOPES