Relationship of thallium-201 myocardial perfusion pattern to regional and global left ventricular function with exercise

Journal Article · Mon Jun 01 04:00:00 EDT 1981 · Am. Heart J.; (United States)

DOI:https://doi.org/10.1016/0002-8703(81)90608-6· OSTI ID:5578557

Kirshenbaum, H D; Okada, R D; Boucher, C A; Kushner, F G; Strauss, H W; Pohost, G M

Thallium-201 redistribution pattern after exercise was related to rest and exercise left ventricular regional and global function, measured by radionuclide ventriculography, in 61 patients, 50 with coronary artery disease (CAD). Sixteen patients had exclusively transient thallium defects, suggesting ischemia: in this group, mean left ventricular ejection fraction (LVEF) was 65% at rest, falling to 58% during exercise (p less than 0.01). Eight patients had exclusively persistent thallium defects, suggesting scar: LVEF was unchanged during exercise, 58% to 59%. LVEF increased during exercise in the 17 patients without exercise thallium defects, seven with CAD: 66% to 73% (p less than 0.05). Individual LV wall segments which exhibited transient or persistent thallium defects contracted abnormally both at rest and during exercise; (2) both transient and persistent thallium defects can be associated with resting dyssynergy; and (3) in some CAD patients, apparent hypoperfusion does not necessarily predict left ventricular dysfunction during exercise.

• OSTI ID: 5578557
• Journal Information: Am. Heart J.; (United States), Journal Name: Am. Heart J.; (United States) Vol. 101:6; ISSN AHJOA
• Country of Publication: United States
• Language: English

Related Subjects

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560171 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ARTERIES
BETA DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CORONARIES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
DISTRIBUTION
ELECTRON CAPTURE RADIOISOTOPES
EXERCISE
HEART
HEAVY NUCLEI
ISCHEMIA
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TISSUE DISTRIBUTION
USES
VASCULAR DISEASES