Low selenium environment and Vitamin E in human serum relative to the Kaschin-Beck's disease (in Chinese)
In China, endemic regions of Kaschin-Beck's disease, Keshan disease, and animal white muscle disease basically overlap, mainly the transitional area between the moist Southeast and the arid Northwest. Tests conducted by the authors reveal that the selenium content of major soils of the regions affected by the diseases is 0.088 to 0.360 ppM, that of the grains below 20 to 30 ppB. Of the inhabitants, 94 percent have serum selenium content below 0.031 ..mu..g/l and the selenium content of the hair of inhabitants is 100 to 200 ppB. From July 1979 to June 1980, the authors treated 41 cases of Kaschin-Beck's disease with sodium selenite-V/sub E/ and 36 of them recovered from the disease. Based upon these data, the authors believe that environmental selenium deficiency of these regions is perhaps the cause of the low level selenium nutrition of the inhabitants. The low level selenium nutrition in turn leads to a reduction of certain enzymic activity to cause the Kaschin-Beck's disease, as well as the Keshan disease and the animal white muscle disease.
- OSTI ID:
- 5983304
- Journal Information:
- J. Environ. Sci.; (United States), Vol. 3:2
- Country of Publication:
- United States
- Language:
- Chinese
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Related Subjects
54 ENVIRONMENTAL SCIENCES
METABOLIC DISEASES
PATHOLOGY
SELENIUM
ECOLOGICAL CONCENTRATION
METABOLISM
CEREALS
DIET
ENZYME ACTIVITY
FOOD CHAINS
HUMAN POPULATIONS
NUTRITION
NUTRITIONAL DEFICIENCY
REGIONAL ANALYSIS
SEEDS
VITAMIN E
DISEASES
ELEMENTS
GRAMINEAE
GRASS
PLANTS
POPULATIONS
SEMIMETALS
VITAMINS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
510302 - Environment
Terrestrial- Radioactive Materials Monitoring & Transport- Terrestrial Ecosystems & Food Chains- (-1987)