Hepatic visualization on iodine-131 whole-body thyroid cancer scans

Journal Article · Tue Sep 01 04:00:00 EDT 1987 · J. Nucl. Med.; (United States)

OSTI ID:5974228

Ziessman, H A; Bahar, H; Fahey, F H; Dubiansky, V

This study examines the frequency and significance of diffuse liver uptake on /sup 131/I whole-body thyroid cancer scans. Sixty whole-body scans on 27 patients with differentiated thyroid cancer were reviewed. Liver uptake was quantitated on another 21 studies (16 patients). Diffuse hepatic uptake was seen in 44% of patients and 35% of all the studies. It correlated best with the /sup 131/I dose administered (r = 0.733) and the product of the /sup 131/I percent radioactive iodine uptake (RAIU) and administered dose (r = 0.656), less well with the serum /sup 131/I protein bound iodine (r = 0.494) and the RAIU. This study demonstrates that liver visualization is more common than generally appreciated and is related to the /sup 131/I dose and indices of thyroid function although other factors may also play a role in liver visualization.

• Research Organization: Georgetown Univ. Medical Center, Washington, DC
• OSTI ID: 5974228
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 28:9; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOTOPES
LIVER
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
THYROID
UPTAKE
WHOLE-BODY COUNTING