Interrelationships of selenium with other trace elements

Journal Article · Wed Oct 01 00:00:00 EDT 1975 · Fed. Proc.; (United States)

OSTI ID:5966341

Hill, C H

Biological interactions between selenium and a number of other elements occur that render selenium much less toxic than when it is present alone. These elements are arsenic, mercury, cadmium, and copper. Furthermore, the presence of selenium reduces the toxicity of mercury and cadmium. These are general biological interactions and have been found to occur in a number of animal species under a variety of conditions. It has been shown that the reaction products of selenium with mercury and cadmium are less toxic than an equal amount of selenium fed alone to chicks. The presence of arsenic shifts the excretion of selenium to the bile. There is no conclusive evidence that the presence of other elements reduces the absorption or retention of selenium. It is possible that some of the interactions are caused by the formation of a compound by selenium and other elements which has less affinity for active groups on biologically active compounds. 33 references, 22 tables.

• Research Organization: North Carolina State Univ., Raleigh
• OSTI ID: 5966341
• Journal Information: Fed. Proc.; (United States), Journal Name: Fed. Proc.; (United States) Vol. 34:11; ISSN FEPRA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ARSENIC
BIOLOGICAL EFFECTS
BIRDS
CADMIUM
CHICKENS
COPPER
ELEMENTS
FOWL
INHIBITION
MERCURY
METALS
RESPONSE MODIFYING FACTORS
SELENIUM
SEMIMETALS
TOXICITY
TRANSITION ELEMENTS
VERTEBRATES