Levels of enzymes involved in the synthesis of acetate from CO/sub 2/ in Clostridium thermoautotrophicum

Journal Article · Thu Jul 01 04:00:00 EDT 1982 · J. Bacteriol.; (United States)

OSTI ID:5964810

Clark, J E; Ragsdale, S W; Ljungdahl, L G; Wiegel, J

The acetogenic bacterium Clostridium thermoautotrophicum, grown on methanol, glucose, or CO/sub 2/-H/sub 2/, contained high levels of corrinoids, formate dehydrogenase, tetrahydrofolate enzymes, carbon monoxide dehydrogenase, and hydrogenase. Cell-free extracts catalyzed pyruvate-dependent formation of acetate form methyltetrahydrofolate. These results suggest that C. thermoautotrophicum synthesizes acetate from CO/sub 2/ via a formate-tetrahydrofolate-corrinoid pathway.

• Research Organization: Univ. of Georgia, Athens
• DOE Contract Number: AS09-79ER10499
• OSTI ID: 5964810
• Journal Information: J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 151:1; ISSN JOBAA
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ACETATES
BACTERIA
BIOCHEMISTRY
BIOSYNTHESIS
CARBON 14 COMPOUNDS
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CARBOXYLIC ACID SALTS
CHALCOGENIDES
CHEMISTRY
CLOSTRIDIUM
ENZYME ACTIVITY
ENZYMES
FORMATES
HYDROGENASES
LABELLED COMPOUNDS
MICROORGANISMS
OXIDES
OXIDOREDUCTASES
OXYGEN COMPOUNDS
SYNTHESIS