A modality-specific neuromagnetic P3

Conference · Sat Dec 31 23:00:00 EST 1988

OSTI ID:5962928

Flynn, E R; Lewine, J D; Oakley, M T; Roeder, S B; Arthur, D L; Aine, C J; George, J S

Several studies indicate that in cases of psychopathology and alcoholism the amplitude and/or latency of endogenous, scalp-recorded P3 potentials elicited by rare events are abnormal. The P3 complex may normally be a valuable index of the brain's work-load and identification of the neural generator(s) of this late positive component would thus provide valuable insight into the substrates of both normal and abnormal information processes. Okada and his colleagues have recorded magnetic field correlates of P3 potentials evoked by visual and auditory stimuli. Data from a mapping study of a visually evoked magnetic P3 were consistent with a hippocampal source, but attempts to localize the generator(s) of the auditory magnetic P3 were unsuccessful. In an effort to independently confirm, extend, and clarify these results, the surface topographies of magnetic P3-like complexes evoked during the performance of auditory and visual detection tasks were examined. 6 refs., 2 figs.

• Research Organization: Los Alamos National Lab., NM (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 5962928
• Report Number(s): LA-UR-89-2221; CONF-890849-4; ON: DE89014468
• Country of Publication: United States
• Language: English

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