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Effects of circular and elliptical 180/sup 0/ acquisition on reconstructed Thallium-201 activity

Conference · · J. Nucl. Med.; (United States)
OSTI ID:5958647
Tomographic myocardial imaging with T1-201 has become an important clinical technique in the evaluation of coronary artery disease. The authors have developed a computer model which simulates both the conventional circular rotation and elliptical rotation where improved resolution is obtained by bringing the camera closer to the body. The model allows for resolution variation with object depth, as well as for the variation in the amount of attenuation with relative camera position. The two dimensional myocardial phantom had constant T1-201 ''uptake''. The heart was embedded in an elliptically shaped thorax phantom, which provided attenuation from chest wall, lungs and heart. Data were acquired over 180/sup 0/, and the uptake of the T1-201 in the walls of the myocardium in the reconstructed transaxial images was quantified though a circumferential analysis. For both the circular and elliptical acquisitions, the model predicts that the reconstructed T1-201 distribution is not uniform. This paper concludes since view dependent attenuation and resolution cannot be deconvolved with available correction methods, clinical T1-201 studies need to be compared with normal data sets.
Research Organization:
Emory Univ. School of Medicine, Atlanta, GA
OSTI ID:
5958647
Report Number(s):
CONF-850611-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
Country of Publication:
United States
Language:
English