Impact of radionuclide techniques on evaluation of patients with ischemic heart disease

Journal Article · Sat Jan 01 04:00:00 EST 1983 · J Am Coll Cardiol; (United States)

DOI:https://doi.org/10.1016/S0735-1097(83)80011-4· OSTI ID:5950627

Pitt, B; Kalff, V; Rabinovitch, M A; Buda, A J; Colfer, H T; Vogel, R A; Thrall, J H

Radiotracer studies of the heart have become clinically important in the last decade, especially for evaluation of patients with known or suspected ischemic heart disease. Radionuclide ventriculography provides quantitative measures of biventricular function and regional wall motion. Recent technical advances include the development of computer programs for analyzing diastolic function, parametric imaging methods such as phase analysis and methods for calculating absolute ventricular volumes. /sup 201/Tl scans provide maps of regional myocardial perfusion. Recent advances include development of computer programs to quantitate regional /sup 201/Tl uptake and to calculate /sup 201/Tl turnover rates and the development of tomographic imaging systems. /sup 99m/Tc pyrophosphate localizes in irreversibly damaged myocardium and provides a method for diagnosing, localizing and sizing acute myocardial infarcts. Recent applications include tomographic imaging to improve image contrast and development of criteria to identify high risk patients after infarction. Two important trends affecting the application of all the radionuclide studies in clinical cardiologic practice are the increasing use of decision analysis for incorporating results of multiple tests into single diagnostic probability statements, and the use of diagnostic algorithms that include the radionuclide studies to optimize the cost effectiveness of evaluation of patients with ischemic heart disease.

• Research Organization: Division of Cardiology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor
• OSTI ID: 5950627
• Journal Information: J Am Coll Cardiol; (United States), Journal Name: J Am Coll Cardiol; (United States) Vol. 1:1
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
HEART
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
TECHNETIUM 99
TECHNETIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES