Process for the extemporaneous preparation of an injectable fatty acid tagged in the omega position by means of radioactive iodine

Patent · Tue Oct 09 04:00:00 EDT 1984

OSTI ID:5939208

Bardy, A; Comet, M; Coornaert, S; Mathieu, J P; Riche, F; Vidal, M

A process is claimed for the preparation of a fatty acid tagged with radioactive iodine, where a brominated or iodized fatty acid is reacted, preferably in the omega position, with radioactive iodide in the dry state or with an aqueous solution of radioactive iodide, in the presence of vehicling iodide, to exchange the bromine or iodine of the fatty acid for radioactive iodine. Application to use as radio-pharmaceutical products for studying cardiac metabolism troubles in human beings by scintigraphy is mentioned.

• Assignee: Commissariat a l'Energie Atomique (France)
• Patent Number(s): US 4476106
• OSTI ID: 5939208
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AQUEOUS SOLUTIONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BROMINATION
BROMINE
CARBOXYLIC ACIDS
CHEMICAL PREPARATION
CHEMICAL REACTIONS
CHEMISTRY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC USES
DISPERSIONS
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
HALOGENATION
HALOGENS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINATION
IODINE
IODINE 123
IODINE 131
IODINE ISOTOPES
ION EXCHANGE
ISOTOPES
LABELLED COMPOUNDS
LABELLING
MIXTURES
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
RADIOCHEMISTRY
RADIOISOTOPES
RADIOPHARMACEUTICALS
SOLUTIONS
SYNTHESIS
USES