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Interaction of blood sex steroid-binding globulin-steroid complexes with the plasma membranes of cells of the human decidual endometrium

Journal Article · · Biochemistry (Engl. Transl.); (United States)
OSTI ID:5933353

The plasma membranes of cells of the decidual tissue specifically bind complexes of the sex steroid-binding globulin (SBG) of the blood with estrogens (estradiol, estriol, estrone) and the pharmacological agent danazol but do not interact with SBG-testosterone and SBG-dihydrotestosterone complexes. The selectivity of the interaction of SBG-steroid complexes with the cell membranes of the decidual tissue confirms the hypothesis of an active role of SBG in the action of steroids on this target tissue.

Research Organization:
Institute of Bioorganic Chemistry, Minsk, USSR
OSTI ID:
5933353
Journal Information:
Biochemistry (Engl. Transl.); (United States), Journal Name: Biochemistry (Engl. Transl.); (United States) Vol. 50:7; ISSN BIORA
Country of Publication:
United States
Language:
English