Biological applications and effects of optical masers. Annual report (final), March 16-October 15, 1986
The literature pertaining to retinal light damage from environmental and man-made optical sources prior to the last decade is reviewed with particular attention to acute and long-term chronic exposure leading to thermal and photochemical lesions of the retina. The parameters of wavelength, exposure time, and power level are given as the major factors defining thermal vs photochemical damage. Light toxicity as a function of wavelength is dealt with in some detail. In particular, wavelengths ranging from 1064 nm to 325 nm in the near-ultraviolet are studied using macaque monkeys. Exposures in the near UV were accomplished using aphakic monkeys (lens removed surgically). The histopathologies of blue light and near-ultraviolet lesions of the retina in the macaque monkey are described. Light damage to the RPE and its possible relationship to aging and macular degeneration is investigated.
- Research Organization:
- Virginia Commonwealth Univ., Richmond (USA)
- OSTI ID:
- 5932151
- Report Number(s):
- AD-A-183462/1/XAB
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CHEMICAL REACTIONS
ELECTROMAGNETIC RADIATION
ELEMENTS
EYES
FACE
HEAD
NEAR ULTRAVIOLET RADIATION
NONMETALS
OPTICAL PROPERTIES
ORGANS
OXYGEN
PHOTOCHEMICAL REACTIONS
PHYSICAL PROPERTIES
RADIATION EFFECTS
RADIATIONS
RETINA
SENSE ORGANS
STANDARDS
TOXICITY
ULTRAVIOLET RADIATION