Idiopathic interstitial pneumonia following bone marrow transplantation: the relationship with total body irradiation

Journal Article · Thu Oct 01 00:00:00 EDT 1981 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(81)90032-8· OSTI ID:5923609

Keane, T J; Van Dyk, J; Rider, W D

Interstitial pneumonia is a frequent and often fatal complication of allogenic bone marrow transplantation. Thirty to 40 percent of such cases are of unknown etiology and have been labelled as cases of idiopathic interstitial pneumonia. Idiopathic cases are more commonly associated with the use of total body irradiation; their occurrence appears to be independent of immunosupression or graft versus host disease. Evidence is presented from the literature suggesting that the development of idiopathic interstitial pneumonia is related to the absolute absorbed dose of radiation to lung. The similarity of idiopathic pneumonia to radiation pneumonitis seen in a different clinical setting is described.

• Research Organization: Ontario Cancer Inst., Toronto, Canada
• OSTI ID: 5923609
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 7:10
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE MARROW
TRANSPLANTS
WHOLE-BODY IRRADIATION
SIDE EFFECTS
GRAFT-HOST REACTION
IMMUNOSUPPRESSION
PNEUMONIA
RADIATION DOSES
RADIOTHERAPY
ANIMAL TISSUES
BODY
DISEASES
DOSES
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
IRRADIATION
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
RESPIRATORY SYSTEM DISEASES
THERAPY
TISSUES
550603* - Medicine- External Radiation in Therapy- (1980-)