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Comparison of N-isopropyl (I-123) p-iodoamphetamine brain scans using Anger camera scintigraphy and single-photon emission tomography

Journal Article · · Radiology; (United States)
 [1]; ; ; ;
  1. New England Deaconess Hospital, Boston, MA
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N-isopropyl (I-123) p-iodoamphetamine (IMP), which is extracted by the brain in proportion to regional blood flow, has been shown to be useful with single-photon emission tomography (SPECT) in the assessment of pathologic states related to blood flow. Because emission tomographic equipment is not yet available at most hospitals, the authors compared IMP brain images obtained with an Anger camera with those obtained by SPECT to determine the usefulness of IMP scintigraphy. Thirty-nine pairs of studies were performed on 12 control patients, 14 patients with stroke, three patients with tumors, and a miscellaneous group of eight patients. Planar scintigraphy showed good correlation with SPECT in determining the presence or absence of abnormality in all patients except one with a very small brain stem infarction that was not detected by planar imaging. Anger images showed poor contrast resolution compared with SPECT images. It is thus expected that SPECT will result in better lesion detection when smaller lesions are studied. Planar scintigraphy is not capable of providing quantitative measurement of regional cerebral blood flow.

OSTI ID:
5898637
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 145:3; ISSN RADLA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINES
BETA DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CAMERAS
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EMBOLI
EMISSION COMPUTED TOMOGRAPHY
GAMMA CAMERAS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
NEOPLASMS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TOMOGRAPHY